The 60GHz millimeter-wave (mmWave) wireless technology is a focus of increasing attention, since its ability to transmit more than Gbps PHY data rate makes it suitable for high-speed, short-range applications such as peer-to-peer synchronization and kiosk terminals. In the case of short-range communication with a range of several tens of centimeters, only terminals present in this communication range will be affect and communication is considered to be on a one-to-one basis. In one-to-one communication, a simpler and more efficient access mechanism is preferable. The ability of current CSMA/CA based MAC, for example MAC of IEEE 802.11 WLAN systems, to achieve high throughput is limited by the low MAC efficiency caused by high signal exchange overhead, such as interframe space (IFS) and acknowledgement. This paper proposes an ACK/NACK mechanism that enhances the throughput in short-range one-to-one communication. The ACK/NACK mechanism uses Negative ACK (NACK) as the acknowledgement policy to reduce the overhead of ACK and the transmitter switches the required acknowledgement policy to ACK based on a switchover threshold. It solves a problem arising from NACK, namely, that NACK has no mechanism for keeping alive. We evaluate the throughput of the ACK/NACK mechanism by both theoretical analysis and computer simulation. The proposed ACK/NACK mechanism is implemented in 65 nm CMOS process (BBIC); we connect this BBIC to a 60 GHz RFIC and exchange frames wirelessly. In this experiment, it is verified that the ACK/NACK mechanism enhances throughput.