In this paper a new electromagnetic (EM) interference analysis is proposed using the total harmonic distortion (THD) measurement of the audio signal by the 900 MHz cordless telephones. The cordless telephone network in 900 MHz was built up to be weak in EM interference. 400 and 800 Hz of the sine-wave signal were used in transmitter (TX) system, and the receiver (RX) system was exposed to the EM interference. The THD value varies as the level of the exposed EM interference changes. The model of the cordless telephone also affects the THD value. By using fluctuation of the THD value depending on the amount of the exposure, the threshold value of the interference electric field strength was derived. Based on the derived threshold value of the electric field strength, validity of the regulation value for low power radio devices by CISPR 22 [CLASS B] and FCC is discussed.