Information transmission among biological neurons is carried out by a complex series of spike signals. The input inter-spike arrival times at a neuron are believed to carry information which the neurons utilize to carry out a task. In this paper, a new scheme which utilizes the input inter-spike intervals (ISI) for decoding an input spike train is proposed. A spike train consists of a sequence on input spikes with various inter-spike times. This decoding scheme can also be used for neurons which have multiple synaptic inputs but for which each synapse receives a single spike within one input time window. The ISI decoding neural network requires only a few neurons. Example applications show the usefulness of the decoding scheme.