Non-homogeneous Poisson Processes (NHPP's) can be applied for analyzing reliability growth models for hardware and/or software. Evaluating the Mean Time Between Failures (MTBF's) for such processes, we can evaluate the present status (the degree of improvement). However, it is difficult to evaluate the MTBF's for such processes analytically except the simplest cases. The so-called instantaneous MTBF's which can be easily evaluated are applied in practice instead of the exact MTBF's. In this paper, we discuss both MTBF's analytically, and derive the conditions for the existence of both exact and instantaneous MTBF's. We further illustrate both MTBF's for the Weibull process and S-shaped reliability growth model numerically.