In this paper, we propose a method to estimate the most resource-consuming disease from electronic claim data based on Labeled Latent Dirichlet Allocation (Labeled LDA). The proposed method models each electronic claim from its medical procedures as a mixture of resource-consuming diseases. Thus, the most resource-consuming disease can be automatically estimated by applying Labeled LDA to the electronic claim data. Although our method is composed of a simple scheme, this is the first trial for realizing estimation of the most resource-consuming disease.