This paper proposes a novel configuration for a wideband single-carrier transmitter using a sub-terahertz frequency. For wideband single-carrier transmission over a bandwidth of several gigahertz, the frequency response non-flatness derived from transmitter components in an operating band seriously deteriorates the transmission quality due to inter-symbol interference. A promising approach to address this problem is equalizing the frequency response non-flatness at the transmitter. The proposed novel configuration has a feedback route for calculating the inverse frequency response and multiplying it with a transmission signal spectrum in the frequency domain. Moreover, we verify that employing the proposed transmitter configuration simplifies the receiver configuration by lowering the calculation complexity to minimize the inter-symbol interference to meet the signal-to-interference-and-noise ratio requirements. To confirm the feasibility of the proposed configuration, the transmission quality obtained using the proposed configuration is measured and evaluated. Experimental results confirm that the proposed configuration improves the error vector magnitude value to over 5 dB for a 10 Gbaud transmission and the transmission data rate of 25 Gbps.