OFDMA femtocells in the macrocellular network of which frequency reuse factor is 1 cause serious interference to macrocell users, while the femtocells improve the performance of indoor users. In this letter, a novel downlink resource allocation algorithm for OFDMA femtocell networks is proposed to reduce interference between the macrocells and the femtocells. This algorithm allocates femtocell subchannels to avoid interference to macrocell users in the femtocell coverage, and minimizes the total transmission power of the femtocell to reduce the negative effect on the performance of the macrocell. Simulation results are provided to present the performance of the proposed algorithm.