Let f be a Boolean function in n variables. The Möbius transform and its converse of f can describe the transformation behaviors between the truth table of f and the coefficients of the monomials in the algebraic normal form representation of f. In this letter, we develop the Möbius transform and its converse into a more generalized form, which also includes the known result given by Reed in 1954. We hope that our new result can be used in the design of decoding schemes for linear codes and the cryptanalysis for symmetric cryptography. We also apply our new result to verify the basic idea of the cube attack in a very simple way, in which the cube attack is a powerful technique on the cryptanalysis for symmetric cryptography.