We review our recent work on ultra-long-haul wavelength division multiplexed (WDM) transmission with high spectral efficiency (SE) employing tight pre-filtering and multi-symbol detection. We start the discussion with a theoretical evaluation of the SE limit of pre-filtered modulation in optical fiber communication systems. We show that pre-filtering induced symbol correlation generates a modulation with memory and thus, a higher SE limit than that of the original memory-less modulation. We also investigate the merits of utilizing the pre-filtering induced symbol correlation with multi-symbol detection to achieve high SE transmission. We demonstrate transoceanic WDM transmission of a pre-filtered polarization division multiplexed return-to-zero quaternary phased shift keying (PDM-RZ-QPSK) modulation format with multi-symbol detection, achieving 419% SE which is higher than the SE limit of the original memory-less PDM-RZ-QPSK format.