A high-speed high-resolution sampling system is the crucial part in wideband radar receivers. A 10.4-GS/s 12-bit wideband sampling system based on TIADC technique is designed in this letter. The acquisition function is implemented on a VPX platform. The storage function is implemented on a standard 19-inch rack server. The sampled data is transmitted at high speed through optical fibers between them. A mixed calibration method based on perfect reconstruction is adopted to compensate channel mismatches of wideband TIADC system. For sinusoidal signals from 100MHz to 5000MHz, more than 46-dB SNDR and 56-dB SFDR can be obtained in this sampling system. This letter provides a high-speed and high-resolution acquisition scheme for direct intermediate frequency sampling wideband digital receivers.