The potential of Software Radio (SR) has been slow to materialize. Born out of the spoils of the Cold War, the SR concept has remained prisoner of its origin, mainly focused on the terminal, and still under considerable military influence. Such narrow perspective does not fit with our long held conviction that SR has far-reaching potential, and much broader application. While some saw it as "simply" freeing us from standards, by allowing the definition of the radio terminal in software (hence Software Defined Radio, SDR), we see it as changing not only the way we think radio systems and networks, but also the way we define and provide the services and adapt the applications that ran on top of them. We discuss here this much broader, all encompassing approach. While the "canonical" SDR approach concentrates on the terminal side, ours covers the whole system, extending through the network into service creation and application development. Instead of settling for defining the radio in software, we envision Re-configuring on demand not only the terminal but also the serving network(s) and the services they provide (hence Re-configurable Radio Systems and Networks). To illustrate aspects of this novel approach, we discuss past and ongoing research in Europe on Re-configurable Radio Systems and Networks, and identify areas requiring further attention.