An output voltage estimation and regulation system for a wireless power transfer (WPT) circuit is proposed. Since the fluctuation of a coupling condition and/or a load may vary the voltage supplied with WPT resulting in a malfunction of wireless-powered devices, the output voltage regulation is needed. If the output voltage is regulated by a voltage regulator in a secondary side of the WPT circuit with fixed input power, the voltage regulator wastes the power to regulate the voltage. Therefore the output voltage regulation using a primary-side control, which adjusts the input power depending on the load and/or the coupling condition, is a promising approach for efficient regulation. In addition, it is desirable to eliminate feedback loop from the secondary side to the primary side from the viewpoint of reducing power dissipation and system complexity. The proposed system can estimate and regulate the output voltage independent of both the coupling and the load variation without the feedback loop. An usable range of the coupling coefficient and the load is improved compared to previous works. The validity of the proposed system is confirmed by the SPICE simulator.