In this paper, an interference rejection combining (IRC) technique is proposed for SFBC-OFDM cellular systems that exhibit multiple carrier frequency offsets (CFOs). The IRC weight and the corresponding value for CFO compensation in the proposed technique are obtained by maximizing the post-SINR, i.e., minimizing both the interference signal and inter-channel interference (ICI) terms caused by multiple CFOs. The performance of the conventional IRC and proposed IRC techniques is evaluated by computer simulation for an SFBC-OFDM cellular system with multiple CFOs.