A robust microphone array for speech enhancement and noise suppression is studied in this paper. To overcome target signal cancellation problem of conventional beamformer caused by array imperfections or reverberation effects of acoustic enclosure, the proposed microphone array adopts an arbitrary model of channel transfer function (TF) relating microphone and speech source. Since the estimation of channel TF itself is often intractable, herein, transfer function ratio (TFR) is estimated instead and used to form a suboptimal beamformer. A robust TFR estimation method is proposed based on signal subspace analysis technique against stationary or slowly varying noise. Experiments using simulated signal and actual signal recorded in a real room illustrate that the proposed method has high performance in adverse environment.