A novel random number generation method based on chaotic sampling of regular waveform is proposed. A high speed IC truly random number generator based on this method is also presented. Simulation and experimental results, verifying the feasibility of the circuit, are given. Numerical binary data obtained according to the proposed method pass the four basic tests of FIPS-140-2, while experimental data pass the full NIST-800-22 random number test suite without post-processing.