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Kazuaki SAWADA Hirokazu NAKAZAWA Shoko TAKENAGA Takeshi HIZAWA Masato FUTAGAWA Fumihiro DASAI Takashi SAKURAI Koichi OKUMURA Toshiaki HATTORI Makoto ISHIDA
To visualize the biochemical distribution two-dimensionally, we invented a solid-state-type ion image sensor that indicates the chemical activity of solutions and cells. The device, which consists of a CCD array covered with a functionalized membrane to detect charge accumulation, is highly sensitive to changes in the concentration and two-dimensional distribution of ions and biomaterials.