An evolutionary algorithm is used to evolve a digital circuit which computes a simple hash function mapping a 16-bit address space into an 8-bit one. The target technology is FPGA, where the search space of the algorithm is made of the combinational functions computed by cells and of the interconnections among cells. The evolutionary technique has been applied to five different interconnection topologies, specified by neighbourhood graphs. This circuit is readily applicable to the design of set-associative cache memories. Possible use of the evolutionary approach presented in the paper for on-line tuning of the function during cache operation is also discussed.