Packet delivery in Proxy Mobile IPv6 (PMIPv6) relies on an anchor node called LMA. All packets sent by a source node reach a receiver node via LMA, even though the two nodes attach to the same MAG. In some scenarios, PMIPv6 results in high delivery latency and processing costs due to this unnecessary detour. To address this issue, several PMIPv6 route optimization schemes have been proposed. However, high signaling costs and excessive delays remain when handover is performed. For this reason, we propose an enhanced PMIPv6 route optimization (EPRO) scheme. In addition, we analyze the performance of the EPRO. Analytical results indicate that the EPRO outperforms previous schemes in terms of signaling overhead and handover latency.