This paper focuses on system level simulation of heterogeneous networks (HetNet). Aiming at the imbalance offloading of macro cell and pico cell under the macro-pico coexistence case, we propose an adaptive cell-specific association strategy for HetNet to ensure that users can be served equitably by both macro cell and pico cell. The traditional cell range expansion (CRE) scheme with bias-based cell association has fixed bias values for all pico cells. Our proposal, on the other hand, sets different thresholds of attached users for all MeNB (macro enhanced node B) and PeNBs (pico enhanced node B), and all cell-specific biases are obtained by the proposed adaptive association strategy according to different cell-specific predefined thresholds. With this strategy, the load imbalance between MeNB and different PeNBs is well alleviated, and hence the entire network performance is elevated. Moreover, due to the newly deployed low-power nodes in HetNets, the achieved spectral efficiency of users, especially for cell edge users, is also affected by the downlink inter-cell interference. The idea we put forward is to combine the frequency and power coordination, and so suppress the inter-cell interference. Finally in this paper, we present some numerical results to verify the effectiveness of our proposed approach.