The Multiple Access Interference (MAI) and the Multipath Fading (MPF) restrict the performance of Code-Division Multiple-Access (CDMA) systems. The Multiuser Detection (MUD) based on Particle Swarm Optimization algorithm (PSO) with Rake processing is proposed in this paper to overcome these obstacles, followed by full details of how to apply the Binary PSO MUD (BPSO-MUD) on a CDMA system. Simulations show that the BPSO-MUD has significantly better performance than the Conventional Detection (CD).