A new transmit permission control scheme applicable in multi-cell communication systems is proposed. In this scheme, by prohibiting the transmissions from the users with relatively high propagation loss to their connecting hub stations, level of multiple access interference is decreased, and hence throughput characteristics are improved. Moreover, we continue our discussion to propose two adaptive forms of the transmit permission control scheme, in which the prohibition condition becomes more intelligent by considering the level of the offered traffic loads to hub stations. These methods are utilized in a slotted Aloha random transmission of the spread spectrum packets, and on the uplinks of a low earth orbit satellite communication system as an example of the multi-cell systems. It is shown that the adaptive schemes exhibits significantly improved characteristics at all offered traffic loads in these systems.