Recently, considerable attention has been devoted to the combination of direct sequence-code division multiple access (DS-CDMA) and multi-carrier (MC) modulation for high bit rate indoor wireless systems. In this work we consider the downlink of a cellular MC DS-CDMA system. In particular, we evaluate the performance of some detection schemes considering typical indoor radio channels. Channel estimation techniques are investigated and an effective sub-channel estimation technique is proposed. Moreover, we compare the performance of two equalization techniques combined with two space diversity combining schemes. The results show that good performance can be obtained by a post-detection diversity selection scheme combined with a MMSE equalization technique; moreover, if a proper guard time is selected, performance is almost independent of the number of paths of the channel's impulse response. Results are given in terms of BER obtained by means of analytical computations and simulations.