The MIMO system can meet the growing demand for higher capacity in wireless communication fields. So far, the authors have reported that, based on channel measurements, uncoded performance of narrowband MIMO spatial multiplexing in indoor line-of-sight (LOS) environments generally outperforms that in non-LOS (NLOS) ones under the same transmit power condition. In space-frequency coded MIMO-OFDM spatial multiplexing, however, we cannot expect high space-frequency diversity gain in LOS environments because of high fading correlations and low frequency selectivity of channels so that the performance may degrade unlike uncoded cases. In this letter, we present the practical performance of coded MIMO-OFDM spatial multiplexing based on indoor channel measurements. The results show that an LOS environment tends to provide lower space-frequency diversity effect whereas the MIMO-OFDM spatial multiplexing performance is still better in the environment compared with an NLOS environment.