The Mobile Agent technology helps in the development of applications in open, distributed and heterogeneous environments such as the Internet and the Web, but it has to answer to the requirements of security and interoperability to achieve wide acceptance. The paper focuses on security and interoperability, and describes a Secure and Open Mobile Agent (SOMA) programming environment where both requirements are main design objectives. On the one hand, SOMA is based on a thorough security model and provides a wide range of mechanisms and tools to build and enforce flexible security policies. On the other hand, the SOMA framework permits to interoperate with different application components designed with different programming styles. SOMA grants interoperability by closely considering compliance with the OMG CORBA and MASIF standards. SOMA has already shown the feasibility and effectiveness of the approach for the development of flexible and adaptive applications in several areas, particularly in network and systems management.