In this paper, we propose an overloaded multiple-input multiple-output (MIMO) signal detection scheme with slab decoding and lattice reduction (LR). The proposed scheme firstly splits the transmitted signal vector into two parts, the post-voting vector composed of the same number of signal elements as that of receive antennas, and the pre-voting vector composed of the remaining elements. Secondly, it reduces the candidates of the pre-voting vector using slab decoding and determines the post-voting vectors for each pre-voting vector candidate by LR-aided minimum mean square error (MMSE)-successive interference cancellation (SIC) detection. From the performance analysis of the proposed scheme, we derive an upper bound of the error probability and show that it can achieve the full diversity order. Simulation results show that the proposed scheme can achieve almost the same performance as the optimal ML detection while reducing the required computational complexity.