A new class of nonlinear filters called Vector Median Rational Hybrid Filters (VMRHF) for multispectral image processing is introduced and applied to color image filtering problems. These filters are based on Rational Functions (RF). The VMRHF filter is a two-stage filter, which exploits the features of the vector median filter and those of the rational operator. The filter output is a result of vector rational function operating on the output of three sub-functions. Two vector median (VMF) sub-filters and one center weighted vector median filter (CWVMF) are proposed to be used here due to their desirable properties, such as, edge and details preservation and accurate chromaticity estimation. Experimental results show that the new VMRHF outperforms a number of widely known nonlinear filters for multispectral image processing such as the Vector Median ilter (VMF) and Distance Directional Filters (DDf) with respect to all criteria used.