Discrimination of D-Amino Acids from L-Amino Acids Using Membrane Impedance Change

Hardwell CHIBVONGODZE; Kenshi HAYASHI; Kiyoshi TOKO

Discrimination of D-Amino Acids from L-Amino Acids Using Membrane Impedance Change

Hardwell CHIBVONGODZE, Kenshi HAYASHI, Kiyoshi TOKO

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There are methods used to test the optical purity of enantiomers; however, most of the simple methods are not precise and more complicated methods are better. As a result, these methods cannot be widely used for industrial purposes. The aim of this research is to design a sensor which can discriminate D-amino acids from L-amino acids. The designed sensor has chiral membranes and uses the technique of impedance change of these chiral membranes to discriminate the amino acids. We used a noise-FFT (Fast Fourier Transform) technique to determine the membrane impedance. When an enantiomer membrane resides in a chiral environment, (E^*), diastereomeric interactions (E^*-D) and (E^*-L) are created, which may differ sufficiently in the arrangement of molecules of the membranes so as to permit the discrimination of optical substances due to the change in membrane characteristics. With increasing concentrations of the amino acids, the membrane resistance changes depended on the optical activity of the amino acids. The results suggest that the impedance changes of the chiral membrane with diastereomeric reaction can be used for the high-performance chemical sensor to measure the optical purity of different substances.

Publication: IEICE TRANSACTIONS on Electronics Vol.E83-C No.7 pp.1028-1034

Publication Date: 2000/07/25

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Type of Manuscript: Special Section PAPER (Special Issue on Organic Molecular Electronics for the 21st Century)

Category: Sensor

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Hardwell CHIBVONGODZE, Kenshi HAYASHI, Kiyoshi TOKO, "Discrimination of D-Amino Acids from L-Amino Acids Using Membrane Impedance Change" in IEICE TRANSACTIONS on Electronics, vol. E83-C, no. 7, pp. 1028-1034, July 2000, doi: .
Abstract: There are methods used to test the optical purity of enantiomers; however, most of the simple methods are not precise and more complicated methods are better. As a result, these methods cannot be widely used for industrial purposes. The aim of this research is to design a sensor which can discriminate D-amino acids from L-amino acids. The designed sensor has chiral membranes and uses the technique of impedance change of these chiral membranes to discriminate the amino acids. We used a noise-FFT (Fast Fourier Transform) technique to determine the membrane impedance. When an enantiomer membrane resides in a chiral environment, (E^*), diastereomeric interactions (E^*-D) and (E^*-L) are created, which may differ sufficiently in the arrangement of molecules of the membranes so as to permit the discrimination of optical substances due to the change in membrane characteristics. With increasing concentrations of the amino acids, the membrane resistance changes depended on the optical activity of the amino acids. The results suggest that the impedance changes of the chiral membrane with diastereomeric reaction can be used for the high-performance chemical sensor to measure the optical purity of different substances.
URL: https://global.ieice.org/en_transactions/electronics/10.1587/e83-c_7_1028/_p

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@ARTICLE{e83-c_7_1028,
author={Hardwell CHIBVONGODZE, Kenshi HAYASHI, Kiyoshi TOKO, },
journal={IEICE TRANSACTIONS on Electronics},
title={Discrimination of D-Amino Acids from L-Amino Acids Using Membrane Impedance Change},
year={2000},
volume={E83-C},
number={7},
pages={1028-1034},
abstract={There are methods used to test the optical purity of enantiomers; however, most of the simple methods are not precise and more complicated methods are better. As a result, these methods cannot be widely used for industrial purposes. The aim of this research is to design a sensor which can discriminate D-amino acids from L-amino acids. The designed sensor has chiral membranes and uses the technique of impedance change of these chiral membranes to discriminate the amino acids. We used a noise-FFT (Fast Fourier Transform) technique to determine the membrane impedance. When an enantiomer membrane resides in a chiral environment, (E^*), diastereomeric interactions (E^*-D) and (E^*-L) are created, which may differ sufficiently in the arrangement of molecules of the membranes so as to permit the discrimination of optical substances due to the change in membrane characteristics. With increasing concentrations of the amino acids, the membrane resistance changes depended on the optical activity of the amino acids. The results suggest that the impedance changes of the chiral membrane with diastereomeric reaction can be used for the high-performance chemical sensor to measure the optical purity of different substances.},
keywords={},
doi={},
ISSN={},
month={July},}

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TY - JOUR
TI - Discrimination of D-Amino Acids from L-Amino Acids Using Membrane Impedance Change
T2 - IEICE TRANSACTIONS on Electronics
SP - 1028
EP - 1034
AU - Hardwell CHIBVONGODZE
AU - Kenshi HAYASHI
AU - Kiyoshi TOKO
PY - 2000
DO -
JO - IEICE TRANSACTIONS on Electronics
SN -
VL - E83-C
IS - 7
JA - IEICE TRANSACTIONS on Electronics
Y1 - July 2000
AB - There are methods used to test the optical purity of enantiomers; however, most of the simple methods are not precise and more complicated methods are better. As a result, these methods cannot be widely used for industrial purposes. The aim of this research is to design a sensor which can discriminate D-amino acids from L-amino acids. The designed sensor has chiral membranes and uses the technique of impedance change of these chiral membranes to discriminate the amino acids. We used a noise-FFT (Fast Fourier Transform) technique to determine the membrane impedance. When an enantiomer membrane resides in a chiral environment, (E^*), diastereomeric interactions (E^*-D) and (E^*-L) are created, which may differ sufficiently in the arrangement of molecules of the membranes so as to permit the discrimination of optical substances due to the change in membrane characteristics. With increasing concentrations of the amino acids, the membrane resistance changes depended on the optical activity of the amino acids. The results suggest that the impedance changes of the chiral membrane with diastereomeric reaction can be used for the high-performance chemical sensor to measure the optical purity of different substances.
ER -