IEICE TRANSACTIONS on Electronics
Organic-Inorganic Hybrid Ultra-Thin Films Applied to Glucose Biosensor
Summary :
Thin film glucose biosensors were fabricated with organic/inorganic hybrid films based on glucose oxidase (GOx) and Prussian Blue nano-clusters. The biosensors composed of hybrid films were characterized by the low operating potential and the advantage to interference-free detection. In this research, we employed two kinds of thin films for GOx immobilization: Langmuir-Blodgett (LB) and self-assembled monolayer (SAM). The LB film immobilizes GOx in its inside through the electrostatic force, while the SAM immobilizes GOx with the covalent bond. The sensors with LB film produced a relatively high current signal, while the non-linear behavior and a low stability were recognized. On the other hand, the sensors with SAM presented a good linear relationship and a very stable performance.
- Publication
- IEICE TRANSACTIONS on Electronics Vol.E94-C No.12 pp.1855-1857
- Publication Date
- 2011/12/01
- Publicized
- Online ISSN
- 1745-1353
- DOI
- 10.1587/transele.E94.C.1855
- Type of Manuscript
- BRIEF PAPER
- Category
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Huihui WANG, Hitoshi OHNUKI, Hideaki ENDO, Mitsuru IZUMI, "Organic-Inorganic Hybrid Ultra-Thin Films Applied to Glucose Biosensor" in IEICE TRANSACTIONS on Electronics,
vol. E94-C, no. 12, pp. 1855-1857, December 2011, doi: 10.1587/transele.E94.C.1855.
Abstract: Thin film glucose biosensors were fabricated with organic/inorganic hybrid films based on glucose oxidase (GOx) and Prussian Blue nano-clusters. The biosensors composed of hybrid films were characterized by the low operating potential and the advantage to interference-free detection. In this research, we employed two kinds of thin films for GOx immobilization: Langmuir-Blodgett (LB) and self-assembled monolayer (SAM). The LB film immobilizes GOx in its inside through the electrostatic force, while the SAM immobilizes GOx with the covalent bond. The sensors with LB film produced a relatively high current signal, while the non-linear behavior and a low stability were recognized. On the other hand, the sensors with SAM presented a good linear relationship and a very stable performance.
URL: https://global.ieice.org/en_transactions/electronics/10.1587/transele.E94.C.1855/_p
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@ARTICLE{e94-c_12_1855,
author={Huihui WANG, Hitoshi OHNUKI, Hideaki ENDO, Mitsuru IZUMI, },
journal={IEICE TRANSACTIONS on Electronics},
title={Organic-Inorganic Hybrid Ultra-Thin Films Applied to Glucose Biosensor},
year={2011},
volume={E94-C},
number={12},
pages={1855-1857},
abstract={Thin film glucose biosensors were fabricated with organic/inorganic hybrid films based on glucose oxidase (GOx) and Prussian Blue nano-clusters. The biosensors composed of hybrid films were characterized by the low operating potential and the advantage to interference-free detection. In this research, we employed two kinds of thin films for GOx immobilization: Langmuir-Blodgett (LB) and self-assembled monolayer (SAM). The LB film immobilizes GOx in its inside through the electrostatic force, while the SAM immobilizes GOx with the covalent bond. The sensors with LB film produced a relatively high current signal, while the non-linear behavior and a low stability were recognized. On the other hand, the sensors with SAM presented a good linear relationship and a very stable performance.},
keywords={},
doi={10.1587/transele.E94.C.1855},
ISSN={1745-1353},
month={December},}
Copy
TY - JOUR
TI - Organic-Inorganic Hybrid Ultra-Thin Films Applied to Glucose Biosensor
T2 - IEICE TRANSACTIONS on Electronics
SP - 1855
EP - 1857
AU - Huihui WANG
AU - Hitoshi OHNUKI
AU - Hideaki ENDO
AU - Mitsuru IZUMI
PY - 2011
DO - 10.1587/transele.E94.C.1855
JO - IEICE TRANSACTIONS on Electronics
SN - 1745-1353
VL - E94-C
IS - 12
JA - IEICE TRANSACTIONS on Electronics
Y1 - December 2011
AB - Thin film glucose biosensors were fabricated with organic/inorganic hybrid films based on glucose oxidase (GOx) and Prussian Blue nano-clusters. The biosensors composed of hybrid films were characterized by the low operating potential and the advantage to interference-free detection. In this research, we employed two kinds of thin films for GOx immobilization: Langmuir-Blodgett (LB) and self-assembled monolayer (SAM). The LB film immobilizes GOx in its inside through the electrostatic force, while the SAM immobilizes GOx with the covalent bond. The sensors with LB film produced a relatively high current signal, while the non-linear behavior and a low stability were recognized. On the other hand, the sensors with SAM presented a good linear relationship and a very stable performance.
ER -
English
