It is generally believed that one major function of the immune system is helping to protect multicellular organisms from foreign pathogens, especially replicating pathogens such as viruses, bacteria and parasites. The relevant events in the immune system are not only the molecules, but also their interactions. The immune cells can respond either positively or negatively to the recognition signal. A positive response would result in cell proliferation, activation and antibody secretion, while a negative response would lead to tolerance and suppression. Depending upon these immune mechanisms, an immune network model (here, we call it the binary immune network) based on the biological immune response network was proposed in our previous work. However, there are some problems like that input and memory were all binary and it did not consider the antigen diversity of immune system. To improve these problems, in this paper we propose a fuzzy immune network model by considering the antigen diversity of immune system that is the most important property to be exhibited in the immune system. As an application, the proposed fuzzy immune network is applied to pattern recognition problem. Computer simulations illustrate that the proposed fuzzy immune network model not only can improve the problems existing in the binary immune network but also is capable of clustering arbitrary sequences of large-scale analog input patterns into stable recognition categories.
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Wei-Dong SUN, Zheng TANG, Hiroki TAMURA, Masahiro ISHII, "An Improved Artificial Immune Network Model" in IEICE TRANSACTIONS on Fundamentals,
vol. E87-A, no. 6, pp. 1632-1640, June 2004, doi: .
Abstract: It is generally believed that one major function of the immune system is helping to protect multicellular organisms from foreign pathogens, especially replicating pathogens such as viruses, bacteria and parasites. The relevant events in the immune system are not only the molecules, but also their interactions. The immune cells can respond either positively or negatively to the recognition signal. A positive response would result in cell proliferation, activation and antibody secretion, while a negative response would lead to tolerance and suppression. Depending upon these immune mechanisms, an immune network model (here, we call it the binary immune network) based on the biological immune response network was proposed in our previous work. However, there are some problems like that input and memory were all binary and it did not consider the antigen diversity of immune system. To improve these problems, in this paper we propose a fuzzy immune network model by considering the antigen diversity of immune system that is the most important property to be exhibited in the immune system. As an application, the proposed fuzzy immune network is applied to pattern recognition problem. Computer simulations illustrate that the proposed fuzzy immune network model not only can improve the problems existing in the binary immune network but also is capable of clustering arbitrary sequences of large-scale analog input patterns into stable recognition categories.
URL: https://global.ieice.org/en_transactions/fundamentals/10.1587/e87-a_6_1632/_p
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@ARTICLE{e87-a_6_1632,
author={Wei-Dong SUN, Zheng TANG, Hiroki TAMURA, Masahiro ISHII, },
journal={IEICE TRANSACTIONS on Fundamentals},
title={An Improved Artificial Immune Network Model},
year={2004},
volume={E87-A},
number={6},
pages={1632-1640},
abstract={It is generally believed that one major function of the immune system is helping to protect multicellular organisms from foreign pathogens, especially replicating pathogens such as viruses, bacteria and parasites. The relevant events in the immune system are not only the molecules, but also their interactions. The immune cells can respond either positively or negatively to the recognition signal. A positive response would result in cell proliferation, activation and antibody secretion, while a negative response would lead to tolerance and suppression. Depending upon these immune mechanisms, an immune network model (here, we call it the binary immune network) based on the biological immune response network was proposed in our previous work. However, there are some problems like that input and memory were all binary and it did not consider the antigen diversity of immune system. To improve these problems, in this paper we propose a fuzzy immune network model by considering the antigen diversity of immune system that is the most important property to be exhibited in the immune system. As an application, the proposed fuzzy immune network is applied to pattern recognition problem. Computer simulations illustrate that the proposed fuzzy immune network model not only can improve the problems existing in the binary immune network but also is capable of clustering arbitrary sequences of large-scale analog input patterns into stable recognition categories.},
keywords={},
doi={},
ISSN={},
month={June},}
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TY - JOUR
TI - An Improved Artificial Immune Network Model
T2 - IEICE TRANSACTIONS on Fundamentals
SP - 1632
EP - 1640
AU - Wei-Dong SUN
AU - Zheng TANG
AU - Hiroki TAMURA
AU - Masahiro ISHII
PY - 2004
DO -
JO - IEICE TRANSACTIONS on Fundamentals
SN -
VL - E87-A
IS - 6
JA - IEICE TRANSACTIONS on Fundamentals
Y1 - June 2004
AB - It is generally believed that one major function of the immune system is helping to protect multicellular organisms from foreign pathogens, especially replicating pathogens such as viruses, bacteria and parasites. The relevant events in the immune system are not only the molecules, but also their interactions. The immune cells can respond either positively or negatively to the recognition signal. A positive response would result in cell proliferation, activation and antibody secretion, while a negative response would lead to tolerance and suppression. Depending upon these immune mechanisms, an immune network model (here, we call it the binary immune network) based on the biological immune response network was proposed in our previous work. However, there are some problems like that input and memory were all binary and it did not consider the antigen diversity of immune system. To improve these problems, in this paper we propose a fuzzy immune network model by considering the antigen diversity of immune system that is the most important property to be exhibited in the immune system. As an application, the proposed fuzzy immune network is applied to pattern recognition problem. Computer simulations illustrate that the proposed fuzzy immune network model not only can improve the problems existing in the binary immune network but also is capable of clustering arbitrary sequences of large-scale analog input patterns into stable recognition categories.
ER -