This paper presents a framework of supporting system for a drug formulation. We designed ontology to represent the related knowledge for reusable and sharing purposes. The designed ontology is applied with operation rules to suggest an appropriate generic drug production based on information of original drug. The system also provides a validation module to preliminarily approve a pharmaceutical equivalence of the suggested result. Preliminary testing with four random samples shows potential to reformulate a generic product by returning a satisfactory and acceptable of the system suggestions for all samples.
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Nopphadol CHALORTHAM, Phuriwat LEESAWAT, Taneth RUANGRAJITPAKORN, Thepchai SUPNITHI, "A Framework of Ontology-Based Tablet Production Supporting System for a Drug Reformulation" in IEICE TRANSACTIONS on Information,
vol. E94-D, no. 3, pp. 448-455, March 2011, doi: 10.1587/transinf.E94.D.448.
Abstract: This paper presents a framework of supporting system for a drug formulation. We designed ontology to represent the related knowledge for reusable and sharing purposes. The designed ontology is applied with operation rules to suggest an appropriate generic drug production based on information of original drug. The system also provides a validation module to preliminarily approve a pharmaceutical equivalence of the suggested result. Preliminary testing with four random samples shows potential to reformulate a generic product by returning a satisfactory and acceptable of the system suggestions for all samples.
URL: https://global.ieice.org/en_transactions/information/10.1587/transinf.E94.D.448/_p
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@ARTICLE{e94-d_3_448,
author={Nopphadol CHALORTHAM, Phuriwat LEESAWAT, Taneth RUANGRAJITPAKORN, Thepchai SUPNITHI, },
journal={IEICE TRANSACTIONS on Information},
title={A Framework of Ontology-Based Tablet Production Supporting System for a Drug Reformulation},
year={2011},
volume={E94-D},
number={3},
pages={448-455},
abstract={This paper presents a framework of supporting system for a drug formulation. We designed ontology to represent the related knowledge for reusable and sharing purposes. The designed ontology is applied with operation rules to suggest an appropriate generic drug production based on information of original drug. The system also provides a validation module to preliminarily approve a pharmaceutical equivalence of the suggested result. Preliminary testing with four random samples shows potential to reformulate a generic product by returning a satisfactory and acceptable of the system suggestions for all samples.},
keywords={},
doi={10.1587/transinf.E94.D.448},
ISSN={1745-1361},
month={March},}
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TY - JOUR
TI - A Framework of Ontology-Based Tablet Production Supporting System for a Drug Reformulation
T2 - IEICE TRANSACTIONS on Information
SP - 448
EP - 455
AU - Nopphadol CHALORTHAM
AU - Phuriwat LEESAWAT
AU - Taneth RUANGRAJITPAKORN
AU - Thepchai SUPNITHI
PY - 2011
DO - 10.1587/transinf.E94.D.448
JO - IEICE TRANSACTIONS on Information
SN - 1745-1361
VL - E94-D
IS - 3
JA - IEICE TRANSACTIONS on Information
Y1 - March 2011
AB - This paper presents a framework of supporting system for a drug formulation. We designed ontology to represent the related knowledge for reusable and sharing purposes. The designed ontology is applied with operation rules to suggest an appropriate generic drug production based on information of original drug. The system also provides a validation module to preliminarily approve a pharmaceutical equivalence of the suggested result. Preliminary testing with four random samples shows potential to reformulate a generic product by returning a satisfactory and acceptable of the system suggestions for all samples.
ER -