Under the framework of traditional power spectrum based feature extraction, in order to extract more discriminative information for playback attack detection, this paper proposes a feature by making use of deep neural network to describe the nonlinear relationship between power spectrum and discriminative information. Namely, constant-Q deep coefficients (CQDC). It relies on constant-Q transform, deep neural network and discrete cosine transform. In which, constant-Q transform is used to convert signal from the time domain into the frequency domain because it is a long-term transform that can provide more frequency detail, deep neural network is used to extract more discriminative information to discriminate playback speech from genuine speech and discrete cosine transform is used to decorrelate among the feature dimensions. ASVspoof 2017 corpus version 2.0 is used to evaluate the performance of CQDC. The experimental results show that CQDC outperforms the existing power spectrum obtained from constant-Q transform based features, and equal error can reduce from 19.18% to 51.56%. In addition, we found that discriminative information of CQDC hides in all frequency bins, which is different from commonly used features.

Clinical researches show that the morbidity of coronary artery disease (CAD) is gradually increasing in many countries every year, and it causes hundreds of thousands of people all over the world dying for each year. As the optical coherence tomography with high resolution and better contrast applied to the lesion tissue investigation of human vessel, many more micro-structures of the vessel could be easily and clearly visible to doctors, which help to improve the CAD treatment effect. Manual qualitative analysis and classification of vessel lesion tissue are time-consuming to doctors because a single-time intravascular optical coherence (IVOCT) data set of a patient usually contains hundreds of in-vivo vessel images. To overcome this problem, we focus on the investigation of the superficial layer of the lesion region and propose a model based on local multi-layer region for vessel lesion components (lipid, fibrous and calcified plaque) features characterization and extraction. At the pre-processing stage, we applied two novel automatic methods to remove the catheter and guide-wire respectively. Based on the detected lumen boundary, the multi-layer model in the proximity lumen boundary region (PLBR) was built. In the multi-layer model, features extracted from the A-line sub-region (ALSR) of each layer was employed to characterize the type of the tissue existing in the ALSR. We used 7 human datasets containing total 490 OCT images to assess our tissue classification method. Validation was obtained by comparing the manual assessment with the automatic results derived by our method. The proposed automatic tissue classification method achieved an average accuracy of 89.53%, 93.81% and 91.78% for fibrous, calcified and lipid plaque respectively.