This study proposes a multiple-output differential-input operational transconductance amplifier-C (MODI OTA-C) filter with an impedance scaler to detect cardiac activity. A ladder-type fifth-orderButterworth low-pass filter with a large time constant and low noise is implemented to reduce coefficient sensitivity and address signal distortion. Moreover, linearized MODI OTA structures with reduced transconductance and impedance scaler circuits for noise reduction are used to achieve a wide dynamic range (DR). The OTA-based circuit is operated in the subthreshold region at a supply voltage of 1 V to reduce the power consumption of the wearable device in long-term use. Experimental results of the filter with a bandwidth of 250 Hz reveal that DR is 57.6 dB, and the harmonic distortion components are below -59 dB. The power consumption of the filter, which is fabricated through a TSMC 0.18 µm CMOS process, is lower than 390 nW, and the active area is 0.135 mm2.