Various mixed-signal very-high-speed integrated circuits have been developed using InP DHBTs. These circuits have been designed for fiber-optic 43 Gbit/s transmissions applications. They include: on the transmitting side, a clocked driver and an EAM driver, as well as a PSBT/DQPSK precoder; on the receiving side, a sensitive decision circuit, a limiting amplifier and an eye monitor. System experiments made possible by these circuits include a 6 Tbit/s transmission on >6000 km distance.