This paper presents a 4-valued content-addressable memory (CAM) for fully parallel template-matching operations in real-time cellular logic image processing with fixed templates. A universal literal is essential to perform a multiple-valued template-matching operation. It is decomposed of a pair of a threshold operation in a CAM cell and a logic-value conversion shared by CAM cells in the same column of a CAM cellular array, which makes a CAM cell function simple. Since a threshold operation together with a 4-valued storage element can be designed by using a single floating-gate MOS transistor, a high-density 4-valued universal-literal CAM with a single-transistor cell can be implemented by using a multi-layer interconnection technology. It is demonstrated that the performance of the proposed CAM is much superior to that of conventional CAMs under the same function.