In this paper, a multiple-valued current-mode (MVCM) circuit based on active-load dual-rail differential logic is proposed for a high-performance arithmetic VLSI system with crosstalk-noise immunity. The use of dual-rail complementary differential-pair circuits (DPCs), whose outputs are summed up by wiring makes it possible to reduce the common-mode noise, and yet enhance the switching speed. By using the diode-connected cross-coupled PMOS active loads, the rapid transition of switching in the DPC is relaxed appropriately, which can also eliminate spiked input noise. It is demonstrated that the noise reduction ratio and the switching delay of the proposed MVCM circuit in a 90 nm CMOS technology is superior to those of the corresponding ordinary implementation.