In this paper, a self optimization beamforming null control (SOBNC) scheme is proposed. There is a need of maintaining signal to interference plus noise ratio (SINR) threshold to control modulation and coding schemes (MCS) in recent technologies like Wi-Fi, Long Term Evolution (LTE) and Long Term Evolution Advanced (LTE-A). Selection of MCS depends on the SINR threshold that allows maintaining key performance index (KPI) like block error rate (BLER), bit error rate (BER) and throughput at certain level. The SOBNC is used to control the antenna pattern for SINR estimation and improve the SINR performance of the wireless communication systems. The nulling comes with a price; if wider nulls are introduced, i.e. more number of nulls are used, the 3dB beam-width and peak side lobe level (SLL) in antenna pattern changes critically. This paper proposes a method which automatically controls the number of nulls in the antenna pattern as per the changing environment based on adaptive-network based fuzzy interference system (ANFIS) to maintain output SINR level higher or equal to the required threshold. Finally, simulation results show a performance superiority of the proposed SOBNC compared with minimum mean square error (MMSE) based adaptive nulling control algorithm and conventional fixed null scheme.