A clamped-bit-line sense amplifier (CBLSA) capable of very high-speed operation in one-transistor (1T) DRAM applications has been developed. Results from an experimental test chip demonstrate that the speed of the new circuit is insensitive to bit-line capacitance. Circuit speed is also found to be insensitive to initial bit-line difference voltage. The CBLSA maintains a low-impedance fixed potential on the bit lines during sensing, virtually eliminating sensitivity to inter-bit-line noise coupling and minimizing power supply bounce during sensing. The new sense amplifier operates at higher speeds than conventional circuits and still dissipates less power.