This paper investigates multiple-valued code-division multiple access (MV-CDMA) techniques and circuits for intra/inter-chip communication to achieve efficient data transmission in VLSI systems. To address the problems caused by interconnection complexity, we transmit multiplexed signals inside LSI systems employing pseudo-random orthogonal m-sequences as information carriers. A new class of multiple-valued CDMA techniques for intra-chip communication is discussed to demonstrate the feasibility of eliminating co-channel interference caused by a propagation delay of signals, e.g., clock skew. This paper describes the circuit configuration and performance evaluation of MV-CDMA systems for intra-chip communication. We first explain the principle of MV-CDMA technique, and then propose a bidirectional current-mode CMOS technique to realize compact correlation circuits for CDMA. Finally, we show the Spice and MATLAB simulation results of MV-CDMA systems, which indicate the excellent capabilities of eliminating co-channel interference.