A single-chip ubiquitous sensor network (USN) system-on-a-chip (SoC) for small program memory size and low power has been proposed and integrated in a 0.18-µm CMOS technology. Proposed single-chip USN SoC is mainly consists of radio for 868/915 MHz, analog building block, complete digital baseband physical layer (PHY) and media access control (MAC) functions. The transceiver's analog building block includes a low-noise amplifier, mixer, channel filter, receiver signal-strength indication, frequency synthesizer, voltage-controlled oscillator, and power amplifier. In addition, digital building block consists of differential binary phase-shift keying (DPSK) modulation, demodulation, carrier frequency offset compensation, auto-gain control, embedded 8-bit microcontroller, and digital MAC function. Digital MAC function supports 128 bit advanced encryption standard (AES), cyclic redundancy check (CRC), inter-symbol timing check, MAC frame control, and automatic retransmission. These digital MAC functions reduce the processing power requirements of embedded microcontroller and program memory size by up to 56%. The cascaded noise figure and sensitivity of the overall receiver are 9.5 dB and -99 dBm, respectively. The overall transmitter achieves less than 6.3% error vector magnitude (EVM). The current consumption is 14 mA for reception mode and 16 mA for transmission mode.