This paper details a unique VLSI design scheme which employs self-timed circuits. A 32-bit 50-MFLOPS data-driven microprocessor has been designed using a self-timed clocking scheme. This high performance data-driven microprocessor with sophisticated functions has been designed by a combination of several kinds of self-timed components. All functional blocks in the microprocessor are driven by self-timed clocks. The microprocessor integrates 700,000 devices in a 14.65 mm14.65 mm die area using double polysilicon double metal 0.8 µm CMOS technology.