We propose an active noise control (ANC) system for reducing periodic noise generated in a high magnetic field such as noise generated from magnetic resonance imaging (MRI) devices (MR noise). The proposed ANC system utilizes optical microphones and piezoelectric loudspeakers, because specific acoustic equipment is required to overcome the high-field problem, and consists of a head-mounted structure to control noise near the user's ears and to compensate for the low output of the piezoelectric loudspeaker. Moreover, internal model control (IMC)-based feedback ANC is employed because the MR noise includes some periodic components and is predictable. Our experimental results demonstrate that the proposed ANC system (head-mounted structure) can significantly reduce MR noise by approximately 30 dB in a high field in an actual MRI room even if the imaging mode changes frequently.

Image Registration can be seen as an optimization problem to find a cost function and then use an optimization method to get its minimum. Normalized mutual information is a widely-used robust method to design a cost function in medical image registration. Its calculation is based on the joint histogram of the fixed and transformed moving images. Usually, only a discrete joint histogram is considered in the calculation of normalized mutual information. The discrete joint histogram does not allow the cost function to be explicitly differentiated, so it can only use non-gradient based optimization methods, such as Powell's method, to seek the minimum. In this paper, a parzen-window based method is proposed to estimate the continuous joint histogram in order to make it possible to derive the close form solution for the derivative of the cost function. With this help, we successfully apply the gradient-based optimization method in registration. We also design a new kernel for the parzen-window based method. Our designed kernel is a second order polynomial kernel with the width of two. Because of good theoretical characteristics, this kernel works better than other kernels, such as a cubic B-spline kernel and a first order B-spline kernel, which are widely used in the parzen-window based estimation. Both rigid and non-rigid registration experiments are done to show improved behavior of our designed kernel. Additionally, the proposed method is successfully applied to a clinical CT-MR non-rigid registration which is able to assist a magnetic resonance (MR) guided microwave thermocoagulation of liver tumors.