The conventional universal filtered-DFT-spread-OFDM (UF-DFTs-OFDM) can drastically improve the out-of-band emission (OOBE) caused by the discontinuity between symbols in the conventional cyclic prefix-based DFTs-OFDM (CP-DFTs-OFDM). However, the UF-DFTs-OFDM degrades the communication quality in a long-delay multipath fading environment due to the frequency-domain ripple derived from the long transition time of the low pass filter (LPF) corresponding to the guard interval (GI). In this paper, we propose an enhanced UF-DFTs-OFDM (eUF-DFTs-OFDM) that achieves significantly low OOBE and high communication quality even in a long-delay multipath fading environment. The eUF-DFTs-OFDM applies an LPF with quite short length in combination with the zero padding (ZP) or the CP process. Then, the characteristics of the OOBE, peak-to-average power ratio (PAPR), and block error rate (BLER) are evaluated by computer simulation with the LTE uplink parameters. The result confirms that the eUF-DFTs-OFDM can improve the OOBE by 22.5dB at the channel-edge compared to the CP-DFTs-OFDM, and also improve the ES/N0 to achieve BLER =10-3 by about 2.5dB for QPSK and 16QAM compared to the UF-DFTs-OFDM. For 64QAM, the proposed eUF-DFTs-ODFDM can eliminate the error floor of the UF-DFTs-OFDM. These results indicate that the proposed eUF-DFTs-OFDM can significantly reduce the OOBE while maintaining the same level of communication quality as the CP-DFTs-OFDM even in long-delay multipath environment.