This work reports a novel power-rail electrostatic discharge (ESD) clamp circuit with parasitic bipolar-junction-transistor (BJT) and channel parallel shunt paths. The parallel shunt paths are formed by delivering a tiny ratio of drain voltage to the gate terminal of the clamp device in ESD events. Under such a mechanism, the proposed circuit achieves enhanced robustness over those of both gate-grounded NMOS (ggNMOS) and the referenced gate-coupled NMOS (gcNMOS). Besides, the proposed circuit also achieves improved fast power-up immunity over that of the referenced gcNMOS. All investigated designs are fabricated in a 65-nm CMOS process. Transmission-line-pulsing (TLP) and human-body-model (HBM) test results have both confirmed the performance enhancements of the proposed circuit. Finally, the validity of the achieved performance enhancements on other trigger circuits is essentially revealed in this work.

Recent studies in protein structure prediction such as AlphaFold have enabled deep learning to achieve great attention on the Drug-Target Affinity (DTA) task. Most works are dedicated to embed single molecular property and homogeneous information, ignoring the diverse heterogeneous information gains that are contained in the molecules and interactions. Motivated by this, we propose an end-to-end deep learning framework to perform Molecular Heterogeneous features Fusion (MolHF) for DTA prediction on heterogeneity. To address the challenges that biochemical attributes locates in different heterogeneous spaces, we design a Molecular Heterogeneous Information Learning module with multi-strategy learning. Especially, Molecular Heterogeneous Attention Fusion module is present to obtain the gains of molecular heterogeneous features. With these, the diversity of molecular structure information for drugs can be extracted. Extensive experiments on two benchmark datasets show that our method outperforms the baselines in all four metrics. Ablation studies validate the effect of attentive fusion and multi-group of drug heterogeneous features. Visual presentations demonstrate the impact of protein embedding level and the model ability of fitting data. In summary, the diverse gains brought by heterogeneous information contribute to drug-target affinity prediction.

In image-based relighting (IBR), users are allowed to control the illumination condition of a scene or an object. A relighting data set (RDS) contains a large number of reference images captured under various directional light sources. This paper proposes a principal component analysis (PCA) based compression scheme that effectively reduces the data volume. Since the size of images is very large, a tiling recursive least square PCA (RLS-PCA) is used. The output of RLS-PCA is a set of eigenimages and the corresponding eigen coefficients. To further compress the data, extracted eigenimages are compressed using transform coding while extracted eigen coefficients are compressed using uniform quantization with entropy coding. Our simulation shows that the proposed approach is superior to compressing reference images with JPEG and MPEG2.