In this paper, we show that without any unproven assumption, there exists a "four" move blackbox simulation perfect zero-knowledge interactive proof system of computational ability for any random self-reducible relation R whose domain is in BPP, and that without any unproven assumption, there exists a "four" move blackbox simulation perfect zero-knowledge interactive proof system of knowledge on the prime factorization. These results are optimal in the light of the round complexity, because it is shown that if a relation R has a three move blackbox simulation (perfect) zero-knowledge interactive proof system of computational ability (or of knowledge), then there exists a probabilistic polynomial time algorithm that on input x ∈ {0, 1}*, outputs y such that (x, y)∈R with overwhelming probability if x ∈dom R, and outputs "⊥" with probability 1 if x dom R.