In this article, a GUI system is proposed to support clinical cardiology examinations. The proposed system estimates “pulmonary artery wedge pressure” based on patients' chest radiographs using an explainable regression-based convolutional neural network. The GUI system was validated by performing an effectiveness survey with 23 cardiology physicians with medical licenses. The results indicated that many physicians considered the GUI system to be effective.

The development of educational informatization makes data privacy particularly important in education. With society's development, the education system is complicated, and the result of education evaluation becomes more and more critical to students. The evaluation process of education must be justice and transparent. In recent years, the Onscreen Marking (OSM) system based on traditional cloud platforms has been widely used in various large-scale public examinations. However, due to the excessive concentration of power in the existing scheme, the mainstream marking process is not transparent, and there are hidden dangers of black-box operation, which will damage the fairness of the examination. In addition, issues related to data security and privacy are still considered to be severe challenges. This paper deals with the above problems by providing secure and private transactions in a distributed OSM assuming the semi-trusted examination center. We have implemented a proof-of-concept for a consortium blockchain-based OSM in a privacy-preserving and auditable manner, enabling markers to mark on the distributed ledger anonymously. We have proposed a distributed OSM system in high-level, which provides theoretical support for the fair evaluation process of education informatization. It has particular theoretical and application value for education combined with blockchain.

In this paper, we present a method of analyzing relationships between items in specific health examination data, as one of the basic researches to address increases of lifestyle-related diseases. We use self-organizing maps, and pick up the data from the examination dataset according to the condition specified by some item values. We then focus on twelve items such as hemoglobin A1c (HbA1c), aspartate transaminase (AST), alanine transaminase (ALT), gamma-glutamyl transpeptidase (γ-GTP), and triglyceride (TG). We generate training data presented to a map by calculating the difference between item values associated with successive two years and normalizing the values of this calculation. We label neurons in the map on condition that one of the item values of training data is employed as a parameter. We finally examine the relationships between items by comparing results of labeling (clusters formed in the map) to each other. From experimental results, we separately reveal the relationships among HbA1c, AST, ALT, γ-GTP and TG in the unfavorable case of HbA1c value increasing and those in the favorable case of HbA1c value decreasing.

To promote effective guidance by health checkup results, this paper predict a likelihood of developing lifestyle-related diseases from health check data. In this paper, we focus on the fluctuation of hemoglobin A1c (HbA1c) value, which deeply connected with diabetes onset. Here we predict incensement of HbA1c value and examine which kind of health checkup item has important role for HbA1c fluctuation. Our experimental results show that, when we classify the subjects according to their gender and triglyceride (TG) fluctuation value, we will effectively evaluate the risk of diabetes onset for each class.

In this paper, we will report on a fiber optic oxygen sensor using fluorescence and its application to clinical examinations. It is based on fluorescence quenching. The quenching ratio of fluorescence is proportional to oxygen partial pressure by Stern-Volmer's formula in which oxygen concentration is estimated from measured emission intensity. We fabricated a microscopic luminous probe using a Solvent Green 5 doped plastic optical fiber coupler. The probes were demonstrated to have certain advantages for example they can be operated in both liquid and gas phases. And also, they are stable to pH and flow velocities. As a clinical application, the probe can reliably measure oxygen concentrations of whole blood in vivo. Moreover, we have clarified various characteristics of this probe.

An annoying problem encountered in automatic seal imprint verification is that for seal imprints may have a lot of variations, even if they are all produced from a single seal. This paper proposes a new automatic seal imprint verification system which adds an imprint quality assessment function to our previous system in order to solve this problem, and also examines the verification performance of this system experimentally. This system consists of an imprint quality assessment process and a verification process. In the imprint quality assessment process, an examined imprint is first divided into partial regions. Each partial region is classified into one of three quality classes (good quality region, poor quality region, and background) on the basis of characteristics of its gray level histogram. In the verification process, only good quality partial regions of an examined imprint are verified with registered one. Finally, the examined imprint is classified as one of two types: a genuine and a forgery. However, as a result of quality assessment, if the partial regions classified as poor quality are too many, the examined imprint is classified as ambiguous" without verification processing. A major advantage of this verification system is that this system can verify seal imprints of various qualities efficiently and accurately. Computer experiments with real seal imprints were performed by using this system, previous system (without image quality assessment function) and document examiners of a bank. The results of these experiments show that this system is superior in the verification performance to our previous system, and has a similar verification performance to that of document examiners (i.e., the experimental results show the effectiveness of adding the image quality assessment function to a seal imprint verification system).