We describe a transmission system having a data rate of 160 Gbit/s based on the RZ-DPSK modulation format. The 160 Gbit/s single-polarization signal is generated by optical time division multiplexing technology using the base rate of 40 Gbit/s. The setup is explained and results are given with a special focus on the stability issue of the transmission system. The pulse source, the optical gate for demultiplexing, the clock recovery and the balanced photo-detector are based on semiconductor components. We present long-term bit error measurements (10 hours) over two different long-haul fiber links. The first link comprises 3106 km standard single mode fiber and uses a PMD mitigation scheme. The other link consists of 4 dispersion managed 80 km fiber spans without the need for an additional PMD compensation. Using EDFA amplification solely and also no FEC, error-free operation was achieved over several hours, only limited by slow drift effects in the laboratory system.