High-resolution time of arrival (TOA) estimation techniques have great promise for the high range resolution required in recently developed radar systems. A widely known super-resolution TOA estimation algorithm for such applications, the multiple-signal classification (MUSIC) in the frequency domain, has been proposed, which exploits an orthogonal relationship between signal and noise eigenvectors obtained by the correlation matrix of the observed transfer function. However, this method suffers severely from a degraded resolution when a number of highly correlated interference signals are mixed in the same range gate. As a solution for this problem, this paper proposes a novel TOA estimation algorithm by introducing a maximum likelihood independent component analysis (MLICA) approach, in which multiple complex sinusoidal signals are efficiently separated by the likelihood criteria determined by the probability density function (PDF) of a complex sinusoid. This MLICA schemes can decompose highly correlated interference signals, and the proposed method then incorporates the MLICA into the MUSIC method, to enhance the range resolution in richly interfered situations. The results from numerical simulations and experimental investigation demonstrate that our proposed pre-processing method can enhance TOA estimation resolution compared with that obtained by the original MUSIC, particularly for lower signal-to-noise ratios.

In this paper, we propose a method to reconstruct current distributions in the human brain from neuromagnetic measurements. The proposed method is based on the weighted lead-field synthetic (WLFS) filtering technique with the weighting factors calculated from the results of previous source space scanning. In this method, in addition to the depth normalization technique, weighting factors of the WLFS are determined by the cost values previously calculated based on the multiple signal classification (MUSIC) scan. We performed computer simulations of this method under noisy measurement conditions and compared the results to those obtained with the conventional WLFS method. The results of the simulations indicate that the proposed method is effective for the reconstruction of the current distributions in the human brain using magnetoencephalographic (MEG) measurements, even if the signal-to-noise ratio of the measured data is relatively low. We applied the proposed method to the magnetoencephalographic data obtained during a mental image processing task that included object recognition and mental rotation operations. The results suggest that the proposed method can extract the neural activity in the extrastriate visual region and the parietal region. These results are in agreement with the results of previous positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) studies.