IEICE TRANSACTIONS on Electronics
Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer
Summary :
Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.
- Publication
- IEICE TRANSACTIONS on Electronics Vol.E106-C No.6 pp.248-252
- Publication Date
- 2023/06/01
- Publicized
- 2022/11/28
- Online ISSN
- 1745-1353
- DOI
- 10.1587/transele.2022OMS0005
- Type of Manuscript
- BRIEF PAPER
- Category
Authors
Satomitsu IMAI
Nihon University
Kazuki CHIDAISYO
Nihon University
Kosuke YASUDA
Nihon University
Keyword
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Satomitsu IMAI, Kazuki CHIDAISYO, Kosuke YASUDA, "Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer" in IEICE TRANSACTIONS on Electronics,
vol. E106-C, no. 6, pp. 248-252, June 2023, doi: 10.1587/transele.2022OMS0005.
Abstract: Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.
URL: https://global.ieice.org/en_transactions/electronics/10.1587/transele.2022OMS0005/_p
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@ARTICLE{e106-c_6_248,
author={Satomitsu IMAI, Kazuki CHIDAISYO, Kosuke YASUDA, },
journal={IEICE TRANSACTIONS on Electronics},
title={Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer},
year={2023},
volume={E106-C},
number={6},
pages={248-252},
abstract={Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.},
keywords={},
doi={10.1587/transele.2022OMS0005},
ISSN={1745-1353},
month={June},}
Copy
TY - JOUR
TI - Microneedle of Biodegradable Polyacid Anhydride with a Capillary Open Groove for Reagent Transfer
T2 - IEICE TRANSACTIONS on Electronics
SP - 248
EP - 252
AU - Satomitsu IMAI
AU - Kazuki CHIDAISYO
AU - Kosuke YASUDA
PY - 2023
DO - 10.1587/transele.2022OMS0005
JO - IEICE TRANSACTIONS on Electronics
SN - 1745-1353
VL - E106-C
IS - 6
JA - IEICE TRANSACTIONS on Electronics
Y1 - June 2023
AB - Incorporating a tool for administering medication, such as a syringe, is required in microneedles (MNs) for medical use. This renders it easier for non-medical personnel to administer medication. Because it is difficult to fabricate a hollow MN, we fabricated a capillary groove on an MN and its substrate to enable the administration of a higher dosage. MN grooving is difficult to accomplish via the conventional injection molding method used for polylactic acid. Therefore, biodegradable polyacid anhydride was selected as the material for the MN. Because polyacid anhydride is a low-viscosity liquid at room temperature, an MN can be grooved using a processing method similar to vacuum casting. This study investigated the performance of the capillary force of the MN and the optimum shape and size of the MN by a puncture test.
ER -
English
