IEICE TRANSACTIONS on Fundamentals
A Full-Flexibility-Guaranteed Pin-Count Reduction Design for General-Purpose Digital Microfluidic Biochips
Summary :
Different from application-specific digital microfluidic biochips, a general-purpose design has several advantages such as dynamic reconfigurability, and fast on-line evaluation for real-time applications. To achieve such superiority, this design typically activates each electrode in the chip using an individual control pin. However, as the design complexity increases substantially, an order-of-magnitude increase in the number of control pins will significantly affect the manufacturing cost. To tackle this problem, several methods adopting a pin-sharing mechanism for general-purpose designs have been proposed. Nevertheless, these approaches sacrifice the flexibility of droplet movement, and result in an increase of bioassay completion time. In this paper, we present a novel pin-count reduction design methodology for general-purpose microfluidic biochips. Distinguished from previous approaches, the proposed methodology not only reduces the number of control pins significantly but also guarantees the full flexibility of droplet movement to ensure the minimal bioassay completion time.
- Publication
- IEICE TRANSACTIONS on Fundamentals Vol.E99-A No.2 pp.570-578
- Publication Date
- 2016/02/01
- Publicized
- Online ISSN
- 1745-1337
- DOI
- 10.1587/transfun.E99.A.570
- Type of Manuscript
- PAPER
- Category
- VLSI Design Technology and CAD
Authors
Trung Anh DINH
Ritsumeikan University
Shigeru YAMASHITA
Ritsumeikan University
Tsung-Yi HO
National Tsing Hua University
Keyword
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Trung Anh DINH, Shigeru YAMASHITA, Tsung-Yi HO, "A Full-Flexibility-Guaranteed Pin-Count Reduction Design for General-Purpose Digital Microfluidic Biochips" in IEICE TRANSACTIONS on Fundamentals,
vol. E99-A, no. 2, pp. 570-578, February 2016, doi: 10.1587/transfun.E99.A.570.
Abstract: Different from application-specific digital microfluidic biochips, a general-purpose design has several advantages such as dynamic reconfigurability, and fast on-line evaluation for real-time applications. To achieve such superiority, this design typically activates each electrode in the chip using an individual control pin. However, as the design complexity increases substantially, an order-of-magnitude increase in the number of control pins will significantly affect the manufacturing cost. To tackle this problem, several methods adopting a pin-sharing mechanism for general-purpose designs have been proposed. Nevertheless, these approaches sacrifice the flexibility of droplet movement, and result in an increase of bioassay completion time. In this paper, we present a novel pin-count reduction design methodology for general-purpose microfluidic biochips. Distinguished from previous approaches, the proposed methodology not only reduces the number of control pins significantly but also guarantees the full flexibility of droplet movement to ensure the minimal bioassay completion time.
URL: https://global.ieice.org/en_transactions/fundamentals/10.1587/transfun.E99.A.570/_p
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@ARTICLE{e99-a_2_570,
author={Trung Anh DINH, Shigeru YAMASHITA, Tsung-Yi HO, },
journal={IEICE TRANSACTIONS on Fundamentals},
title={A Full-Flexibility-Guaranteed Pin-Count Reduction Design for General-Purpose Digital Microfluidic Biochips},
year={2016},
volume={E99-A},
number={2},
pages={570-578},
abstract={Different from application-specific digital microfluidic biochips, a general-purpose design has several advantages such as dynamic reconfigurability, and fast on-line evaluation for real-time applications. To achieve such superiority, this design typically activates each electrode in the chip using an individual control pin. However, as the design complexity increases substantially, an order-of-magnitude increase in the number of control pins will significantly affect the manufacturing cost. To tackle this problem, several methods adopting a pin-sharing mechanism for general-purpose designs have been proposed. Nevertheless, these approaches sacrifice the flexibility of droplet movement, and result in an increase of bioassay completion time. In this paper, we present a novel pin-count reduction design methodology for general-purpose microfluidic biochips. Distinguished from previous approaches, the proposed methodology not only reduces the number of control pins significantly but also guarantees the full flexibility of droplet movement to ensure the minimal bioassay completion time.},
keywords={},
doi={10.1587/transfun.E99.A.570},
ISSN={1745-1337},
month={February},}
Copy
TY - JOUR
TI - A Full-Flexibility-Guaranteed Pin-Count Reduction Design for General-Purpose Digital Microfluidic Biochips
T2 - IEICE TRANSACTIONS on Fundamentals
SP - 570
EP - 578
AU - Trung Anh DINH
AU - Shigeru YAMASHITA
AU - Tsung-Yi HO
PY - 2016
DO - 10.1587/transfun.E99.A.570
JO - IEICE TRANSACTIONS on Fundamentals
SN - 1745-1337
VL - E99-A
IS - 2
JA - IEICE TRANSACTIONS on Fundamentals
Y1 - February 2016
AB - Different from application-specific digital microfluidic biochips, a general-purpose design has several advantages such as dynamic reconfigurability, and fast on-line evaluation for real-time applications. To achieve such superiority, this design typically activates each electrode in the chip using an individual control pin. However, as the design complexity increases substantially, an order-of-magnitude increase in the number of control pins will significantly affect the manufacturing cost. To tackle this problem, several methods adopting a pin-sharing mechanism for general-purpose designs have been proposed. Nevertheless, these approaches sacrifice the flexibility of droplet movement, and result in an increase of bioassay completion time. In this paper, we present a novel pin-count reduction design methodology for general-purpose microfluidic biochips. Distinguished from previous approaches, the proposed methodology not only reduces the number of control pins significantly but also guarantees the full flexibility of droplet movement to ensure the minimal bioassay completion time.
ER -
English
