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Spatial and Anatomical Regularization Based on Multiple Kernel Learning for Neuroimaging Classification

YingJiang WU, BenYong LIU

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Summary :

Recently, a high dimensional classification framework has been proposed to introduce spatial and anatomical priors in classical single kernel support vector machine optimization scheme, wherein the sequential minimal optimization (SMO) training algorithm is adopted, for brain image analysis. However, to satisfy the optimization conditions required in the single kernel case, it is unreasonably assumed that the spatial regularization parameter is equal to the anatomical one. In this letter, this approach is improved by combining SMO algorithm with multiple kernel learning to avoid that assumption and optimally estimate two parameters. The improvement is comparably demonstrated by experimental results on classification of Alzheimer patients and elderly controls.

Publication
IEICE TRANSACTIONS on Information Vol.E99-D No.4 pp.1272-1274
Publication Date
2016/04/01
Publicized
2016/01/13
Online ISSN
1745-1361
DOI
10.1587/transinf.2015EDL8163
Type of Manuscript
LETTER
Category
Biological Engineering

Authors

YingJiang WU
  Guizhou University,Guangdong Medical University
BenYong LIU
  Guizhou University

Keyword